Dr. Molly Maloof

Physician & Longevity Expert

Dr. Molly Maloof

Physician & Longevity Expert

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Biography

Molly Maloof, MD delivers science-backed, soul-stirring keynotes on longevity, energy optimization, women’s vitality, human connection, and the future of medicine. She pioneered the first course on healthspan extension at Stanford entitled, “Live Better Longer: Extending Healthspan for Longer Lifespan.” That course—focusing on mitochondrial health, mastering insulin resistance, biofeedback technologies, and lifestyle medicine—became the basis for her bestselling book, The Spark Factor, published by Harper Wave. Today, she brings that same evidence-based insight to audiences around the world.

Dr. Molly is a physician, author, and entrepreneur who lives at the intersection of cutting-edge science, human flourishing, and inspired action. She has spoken at over 50 global conferences and summits from the United Nations and Stanford to The Milken Institute, DLD, Salesforce Dreamforce, Wired Health, A4M, and Singularity University.

She doesn't just deliver brilliant talks—she sparks movements. Her signature keynotes guide audiences from sick care to self-empowerment and from longevity myths to actionable healthspan upgrades.

From financial advisors to biohackers, from wellness executives to visionary investors—Dr. Molly bridges the hard science of medicine with the emotional intelligence of storytelling.

Whether it’s a corporate summit, wellness retreat, or innovation forum, she leaves people thinking differently—and feeling deeply. If you’re looking for a speaker who can energize your audience, elevate your content, and leave people changed—Dr. Molly is ready to deliver.

Speech Topics

Health is Capacity: Investing in Energy for Lifelong Vitality

What if we approached health the same way we approach wealth—intentionally, proactively, and with a strategy for compounding returns? Dr. Molly helps financial professionals and business leaders understand how optimizing physical and emotional energy directly impacts longevity, productivity, and life satisfaction.

Just as wealth managers guide clients in protecting and growing their financial portfolios, Dr. Molly Maloof teaches audiences how to invest in their biological capital—energy. In this transformative keynote, she reframes health as capacity—the cellular, emotional, and existential energy we need not just to survive, but to thrive.

In this visionary keynote, Dr. Molly Maloof, physician, Stanford faculty alum, and author of The Spark Factor, redefines health as human energy capacity—the fundamental asset that fuels not just performance and longevity, but purpose and joy.

Speaking directly to financial advisors, life insurance leaders, and investment professionals, Dr. Molly draws powerful parallels between building metabolic capacity and financial wellness. Just as financial portfolios are built to endure, diversify, and grow, so too can biological systems be optimized to increase resilience, clarity, and lifespan. This talk is particularly resonant for financial advisors, life insurance professionals, and anyone guiding clients through long-term planning.

Key Concepts Covered:

1. Health is Your Biological Balance Sheet
Mitochondria—the energy-producing engines in our cells—are the body’s financial institutions. ATP is the currency. Your ability to thrive depends on how well you invest in and protect this capital. Nutrition, sleep, exercise, and stress reduction become forms of compound interest.

2. Relationships Are Your Emotional Assets
Energy doesn’t just come from food—it comes from connection. Backed by psychoneuroimmunology and the Harvard Grant Study, Molly explains how relationships regulate nervous system safety, reduce disease risk, and create emotional liquidity—especially important for women, caregivers, and aging populations.

3. Purpose Is Your Driving Force
Direction matters. Without a meaningful goal, energy dissipates. Molly shows how to help clients align their health investments with their values, long-term goals, and legacy—just like financial advisors help them align wealth with purpose.

4. Aligning Health & Wealth: The New Advisor Mindset
Whether you’re selling life insurance or advising high-net-worth clients, you’re not just helping them live longer—you’re helping them live better. Learn how to frame healthspan as an investment opportunity, integrate health incentives into planning tools, and empower women to make long-view, self-honoring decisions.

Key Takeaways:

The future of insurance is health-aligned incentives
Healthspan = ability to adapt and generate energy
Metabolic flexibility as a metaphor for financial resilience
Tools for engaging female clients in long-term health & wealth planning

Biohacking the Human Operating System: From Wearables to Wisdom

In this cutting-edge keynote, Dr. Molly Maloof—physician, entrepreneur, and author of The Spark Factor—takes audiences on a guided journey through the science, technology, and soul of human flourishing.

A trusted advisor to over 50 companies in digital health, wearables, and biotech, Dr. Molly distills the latest in regenerative medicine, health optimization tools and longevity innovations into a framework that makes radical wellness practical.

Combining ancient principles with next-gen tools, she redefines biohacking as a return to nature, powered by data. Audiences walk away understanding their bodies like never before—and inspired to integrate both personal and professional longevity strategies into everyday life.

Key Concepts Explored

1. The Body as Operating System
From the brain to the microbiome, Dr. Molly breaks down how core “hardware” systems (the body and its organs, cells and organells; how food and movement directs our structure) and “software” inputs (circadian rhythms, environment, relationships, media diet, thoughts, feelings, emotions) shape healthspan and vitality.

2. Quantified Self, Qualified Life
Explore the most meaningful metrics from CGMs, HRV trackers, ketone monitors, and beyond. Learn how to translate wearable data into wisdom for real behavior change and performance tuning.

3. Metabolic Flexibility is the New Fitness
Learn why building the capacity to switch between fat and carbohydrate metabolism is a cornerstone of resilience. Discover how fasting, carb cycling, cold exposure, and breathwork can be used to train this skill.

4. Hormone-Aware Health Optimization
Understand how to support thyroid, adrenal, and sex hormones through the lens of stress adaptation, circadian rhythm, and personalized nutrition—especially in high-performing men and women.

5. Ancient Signals, Modern Science
Sunlight, grounding, rest, nutrient density, deep love, and purpose aren’t fringe—they are foundational. Molly explains how first principles of vitality still outperform the newest pill if applied consistently.

Mitochondrial Medicine: The Hidden Engine of Human Health

Chronic fatigue. Burnout. Hormonal dysregulation. Mood instability. Weight gain. These aren’t mysteries—they’re mitochondrial symptoms.

In this illuminating keynote, physician and healthspan specialist Dr. Molly Maloof reveals how mitochondrial dysfunction lies at the heart of many modern health challenges—and why optimizing cellular energy is the missing link in both prevention and personalized treatment.

Blending clinical science, female-focused protocols, and the emerging field of biooptimization medicine, Dr. Molly translates complex systems biology into practical strategies that empower clinicians to help their patients reclaim vitality, improve resilience, and slow aging.

Key Concepts Covered:

1. Mitochondria as Clinical Command Centers
Explore how these tiny organelles influence everything from hormone production and immune response to mood, metabolism, and cognition. Understand why dysfunction here underlies conditions like fatigue, depression, insulin resistance, and neuroinflammation.

2. The HPA Axis & Burnout Biology
See how chronic stress rewires mitochondrial signaling, depletes adrenal capacity, and contributes to hormonal collapse—especially in women. Learn about HPA axis dysfunction, the Cell Danger Response, and how to restore the body back to safety with biological and psychological healing modalities.

3. The Female Mitochondrial Blueprint
Women’s mitochondria respond differently to stress, estrogen loss, and oxidative burden. From perimenopause to postmenopause, Dr. Molly walks through protocols to preserve oocyte quality, prevent vascular aging, and improve mood, libido, and energy.

4. The Clinical Tools for Energy Restoration
Understand how to integrate metabolic lab testing, HRV, sleep and stress markers, CGM data, and targeted supplements (like MitoQ, magnesium, and phosphatidylcholine) to personalize care plans for mitochondrial repair.

5. New Paradigm: Energy Deficiency Precedes Disease
Pathology often emerges not from bad genes—but from a loss of bioenergetic capacity. Learn to assess organ reserve, oxidative stress, and functional capacity before full-blown disease manifests.

The Spark Factor

Learn how to heal metabolic dysfunction and harness energy, love, and purpose for lifelong vitality. Based on her book The Spark Factor.

Investing in Health

A science-backed roadmap to human flourishing through investing in physical and financial wellness through the lens of metabolism, relationships, and meaning.

Radical Healthspan Extension

Based on her years teaching Stanford Medical students about the science of healthspan, this keynote explores why living longer isn’t enough—and how we can live better, longer.